Reference SummarySmith RS, Comp Med 2002 Feb;52(1):68-72
Title |
Intraocular teratoma in a mouse. | ||||
Authors |
Smith RS; Miller JV; Sundberg JP | ||||
Journal |
Comp Med | ||||
Volume |
52 | ||||
Issue |
1 | ||||
Year |
2002 | ||||
Pages |
68-72 | ||||
Abstract |
A 4.5-month-old male B6.129S2-Trp53tm1Tyj mouse developed an enlarged left eye. After euthanasia, the eye was removed and found to contain a teratoma composed of smooth muscle, white fat, neural tissue, and villous intestinal epithelium with appearance similar to that of the small intestine. Many normal intraocular structures were absent. To our knowledge, this represents the first reported intraocular teratoma in a mouse. | ||||
Links |
J:75056 – MGI References 11900416 – National Library of Medicine/PubMed |
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Strain Notes
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| Strain | Model Name | Treatment Agent(s) | Organ Affected | Frequency | Model Details |
|---|---|---|---|---|---|
| B6.129S2-Trp53tm1Tyj/J | Testis - Germ cell teratoma | Eye |
observed |