Strain Summary129-Trp53^tm1Tyj/J

Strain Name	129-Trp53^tm1Tyj/J
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	129 Trp53-/- • 129-Trp53-/- • 129 Trp53 null • 129-Trp53tm1Tyj • 129Trp53^tm1Tyj • 129 P53 -/- • 129S1/SvImJ-Trp53^tm1Tyj • 129S3/SvImJ-Trp53^tm1Tyj • 129S3/SvImJ-Trp53^tm1Tyj • 129/Sv p53 (-/-) • p53 -/- • Trp53-null 129-Trp53tm1Tyj
Description	Homozygous mice
Strain Links	• JAX Mice
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Tyj allele Trp53^tm1Tyj / Trp53^tm1Tyj

Models
7 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Blood vessel hemangiosarcoma	Blood vessel	crocidolite asbestos				observed	References: Marsella JM, Environ Health Perspect 1997 Sep;105 Suppl 5():1069-72
Blood vessel hemangiosarcoma	Blood vessel					observed	References: Marsella JM, Environ Health Perspect 1997 Sep;105 Suppl 5():1069-72
Leukocyte lymphoma	Thymus	crocidolite asbestos				observed	References: Marsella JM, Environ Health Perspect 1997 Sep;105 Suppl 5():1069-72
Leukocyte lymphoma	Thymus					observed	References: Marsella JM, Environ Health Perspect 1997 Sep;105 Suppl 5():1069-72
Mesothelium mesothelioma - malignant	Mesothelium	crocidolite asbestos				12.5	References: Marsella JM, Environ Health Perspect 1997 Sep;105 Suppl 5():1069-72
Mesothelium mesothelioma - malignant	Mesothelium					0	References: Marsella JM, Environ Health Perspect 1997 Sep;105 Suppl 5():1069-72
(Unspecified organ) tumor	(Unspecified organ)					100	References: Ayanga B, Genes Chromosomes Cancer 2006 Jul;45(7):668-75

Models