Strain SummaryC57BL/6-ApcMin/+
Strain Name |
C57BL/6-ApcMin/+ |
Strain Type(s) |
chemically induced mutation |
Strain Synonym(s) |
APCMin-/+ • APC-/+ • B6 ApcMin/+ • B6-ApcMin • B6 Min/+ • C57/Bl6 APC-/+ • C57BL/6 ApcMin/+ • C57BL/6-ApcMin/+ • C57BL/6 Min/+ • C57Bl/6J-ApcMin • ApcMin/+ • ApcMin/+ +/+ • ApcMin • ApcMin/+ • ApcMin heterozygote • Min • Min/+ • Min/+ |
Description |
Heterozygous mice - "Min" mutation, background is C57BL/6 (substrain(s) unspecified). |
Strain Genetics |
ApcMin / Apc+ |
Pla2g2aMom1-s / Pla2g2aMom1-s |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon hyperplasia | Intestine - Large Intestine - Colon | piroxicam |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon | piroxicam |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 |
||||
Intestine - Large Intestine - Colon tumor | Intestine - Large Intestine - Colon |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 |
|||||
Intestine - Large Intestine adenoma | Intestine - Large Intestine | aspirin (acetylsalicylic acid) (ASA) |
observed |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
||||
Intestine - Large Intestine adenoma | Intestine - Large Intestine |
22 - 33 |
References: Ahn B, Cancer Res 2001 Dec 1;61(23):8357-60 |
|||||
Intestine - Large Intestine adenoma | Intestine - Large Intestine | aminoguanidine hemisulfate |
50 |
References: Ahn B, Cancer Res 2001 Dec 1;61(23):8357-60 |
||||
Intestine - Large Intestine adenoma | Intestine - Large Intestine | L-arginine-deficient (Harlan Teklad TD 91230) |
33 |
References: Ahn B, Cancer Res 2001 Dec 1;61(23):8357-60 |
||||
Intestine - Large Intestine carcinoma - polypoid | Intestine - Large Intestine |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
|||||
Intestine - Large Intestine carcinoma - polypoid | Intestine - Large Intestine | omeprazole |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine - Large Intestine tumor | Intestine - Large Intestine |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 ⋅ Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
|||||
Intestine - Large Intestine tumor | Intestine - Large Intestine | 16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) |
observed |
References: Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
||||
Intestine - Large Intestine tumor | Intestine - Large Intestine | omeprazole |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine - Large Intestine tumor | Intestine - Large Intestine | omeprazole ⋅ rat Gastrimmune |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine - Large Intestine tumor | Intestine - Large Intestine | rat Gastrimmune |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine - Small Intestine - Duodenum tumor | Intestine - Small Intestine - Duodenum | piroxicam |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 |
||||
Intestine - Small Intestine - Duodenum tumor | Intestine - Small Intestine - Duodenum |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 ⋅ Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
|||||
Intestine - Small Intestine - Duodenum tumor | Intestine - Small Intestine - Duodenum | 16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) |
observed |
References: Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
||||
Intestine - Small Intestine - Ileum tumor | Intestine - Small Intestine - Ileum |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 ⋅ Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
|||||
Intestine - Small Intestine - Ileum tumor | Intestine - Small Intestine - Ileum | 16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) |
observed |
References: Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
||||
Intestine - Small Intestine - Jejunum tumor | Intestine - Small Intestine - Jejunum |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 ⋅ Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
|||||
Intestine - Small Intestine - Jejunum tumor | Intestine - Small Intestine - Jejunum | 16,16-dimethyl-prostaglandin E2 (16,16dmPGE2) |
observed |
References: Wilson JW, Cancer Res 2000 Aug 15;60(16):4645-53 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | aspirin (acetylsalicylic acid) (ASA) |
observed - 69 |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine |
observed |
observed |
References: Ahn B, Cancer Res 2001 Dec 1;61(23):8357-60 ⋅ Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | aminoguanidine hemisulfate |
observed |
References: Ahn B, Cancer Res 2001 Dec 1;61(23):8357-60 |
||||
Intestine - Small Intestine adenoma | Intestine - Small Intestine | L-arginine-deficient (Harlan Teklad TD 91230) |
observed |
References: Ahn B, Cancer Res 2001 Dec 1;61(23):8357-60 |
||||
Intestine - Small Intestine tumor | Intestine - Small Intestine |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
|||||
Intestine - Small Intestine tumor | Intestine - Small Intestine | omeprazole |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine - Small Intestine tumor | Intestine - Small Intestine | omeprazole ⋅ rat Gastrimmune |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine - Small Intestine tumor | Intestine - Small Intestine | rat Gastrimmune |
observed |
References: Watson SA, Cancer Res 2001 Jan 15;61(2):625-31 |
||||
Intestine adenoma | Intestine |
observed |
observed - 100 |
References: Haigis KM, Nat Genet 2003 Jan;33(1):33-9 ⋅ Laird PW, Cell 1995 Apr 21;81(2):197-205 ⋅ Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
||||
Intestine adenoma | Intestine | aspirin (acetylsalicylic acid) (ASA) |
100 |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
||||
Intestine adenoma | Intestine | 5-aza-2'-deoxycytidine (5-aza-dC) (decitabine) (DAC) |
observed |
References: Laird PW, Cell 1995 Apr 21;81(2):197-205 |
||||
Intestine tumor | Intestine |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 |
|||||
Intestine tumor | Intestine | piroxicam |
observed |
References: Ritland SR, Carcinogenesis 1999 Jan;20(1):51-8 |
||||
Leukocyte lymphoma | Leukocyte | aspirin (acetylsalicylic acid) (ASA) |
observed |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
||||
Leukocyte lymphoma | Leukocyte |
observed |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
|||||
Mammary gland acanthoma | Mammary gland |
6.7 |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |
|||||
Mammary gland acanthoma | Mammary gland | aspirin (acetylsalicylic acid) (ASA) |
0 |
References: Sansom OJ, Cancer Res 2001 Oct 1;61(19):7060-4 |