Strain SummaryFVB/N-Tg(MMTVneu)202Mul

Strain Name	FVB/N-Tg(MMTVneu)202Mul
Strain Type(s)	transgenic
Strain Synonym(s)	FVB-neu • FVB-MMTV-neu • FVB-NeuN • FVB-NeuN N#202 • FVB/N-Tg(MMTVneu)202Mul/J • FVB/N-TgN(MMTVneu)202Mul • HER-2/neu • HER-2/neu proto-oncogene • neu/ERBB2 • neu protooncogene • line N# 202 MMTV-neu • MMTV-c-neu • MMTV-neu • MMTV/neu • MMTV-Neu • MMTV-neu (line 202) • MMTVneuN • MMTV/unactivated neu • N#202 • Neu.FVB • No. 202 line • unactivated neu • wild-type rat c-neu line 22 [sic]
Description	Transgenic mice carrying an unactivated rat Erbb2 cDNA sequence under the control of the MMTV promoter.
Strain Genetics	List all models in MMHCdb carrying the Tg(MMTVneu)202Mul allele Tg(MMTVneu)202Mul
	List all models in MMHCdb carrying the H2^q allele H2^q / H2^q

Models
8 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Mammary gland adenocarcinoma	Mammary gland		observed - 79				References: Guy CT, Proc Natl Acad Sci U S A 1992 Nov 15;89(22):10578-82 ⋅ Li B, Mol Cell Biol 1997 Jun;17(6):3155-63 ⋅ Ritland SR, Cancer Res 1997 Aug 15;57(16):3520-5 ⋅ Rudolph-Owen LA, Cancer Res 1998 Dec 1;58(23):5500-6 ⋅ Trimble MS, Oncogene 1993 Nov;8(11):3037-42 Sites of Metastasis: Lung
Mammary gland carcinoma	Mammary gland		observed - 100				References: Boggio K, J Exp Med 1998 Aug 3;188(3):589-96 ⋅ Di Carlo E, Lab Invest 1999 Oct;79(10):1261-9 Sites of Metastasis: Lung
Mammary gland carcinoma	Mammary gland	interleukin 12 (IL-12)	50				References: Boggio K, J Exp Med 1998 Aug 3;188(3):589-96
Mammary gland carcinoma in situ	Mammary gland		observed				References: Boggio K, J Exp Med 1998 Aug 3;188(3):589-96
Mammary gland hyperplasia - atypical	Mammary gland		0 - observed				References: Boggio K, J Exp Med 1998 Aug 3;188(3):589-96 ⋅ Di Carlo E, Lab Invest 1999 Oct;79(10):1261-9
Mammary gland hyperplasia - cystic	Mammary gland		observed				References: Trimble MS, Oncogene 1993 Nov;8(11):3037-42
Mammary gland tumor	Mammary gland		64 - 100				References: Landis MD, Oncogene 2006 Jun 1;25(23):3325-34 ⋅ Rowse GJ, Cancer Res 1998 Jun 15;58(12):2675-9
Mammary gland tumor - solid	Mammary gland		observed				References: Landis MD, Oncogene 2006 Jun 1;25(23):3325-34 Sites of Metastasis: Lung

Models