Model DetailsLiver - Hepatocyte hyperplasia

Model Name

Liver - Hepatocyte hyperplasia

Strain

CD-1

Tumor Inducing Agent(s)

Chemical/Drug : piperonyl butoxide (alpha-[2-(2-butoxyethoxy)ethoxy-4,5-methylenedioxy-2-propyltoluene)

Tumor Synonym

hepatocellular hyperplasia

Strain Synonyms

outbred CD-1  •  Swiss CD-1®  •  CD1 nontransgenic  •  Charles River CD-1  •  Swiss CD-1  •  Crl:CD-1®(ICR)  •  outbred CD1  •  (Swiss) CD-1  •  CD1  •  Crl:CD-1(ICR)BR  •  ICR Crj:CD-1  •  random-bred Crl:CD-1(ICR)BR  •  CD-1 outbred  •  Crl:CD-1 (ICR) BR  •  Crj:CD-1(ICR)  •  ICR(CD-1)  •  Crl: CD-1 (ICR) BR  •  ICR
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Liver - Hepatocyte Male

38%

(20 of 52 mice)
57 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Takahashi O, Toxicology 1997 Dec 26;124(2):95-103
Liver - Hepatocyte Male

9.9%

(8 of 81 mice)
57 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Takahashi O, Toxicology 1997 Dec 26;124(2):95-103
Liver - Hepatocyte Female

14%

(7 of 50 mice)
57 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Takahashi O, Toxicology 1997 Dec 26;124(2):95-103
Liver - Hepatocyte Female

32%

(20 of 63 mice)
57 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Takahashi O, Toxicology 1997 Dec 26;124(2):95-103