Model DetailsUrinary bladder transitional cell carcinoma
Model Name |
Urinary bladder transitional cell carcinoma | Strain |
B6.129S7-Trp53tm1Brd/+ |
Tumor Inducing Agent(s) |
Chemical/Drug : N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) |
Tumor Synonyms |
transitional cell carcinoma (TCC) of the bladder • bladder carcinoma • transitional cell carcinoma of the urinary bladder |
Strain Synonyms |
C57BL/6-Trp53tm1Bay/+ • p53+/- • heterozygote p53 knockout • p53-deficient • p53(+/-) • TSG-p53(+/-) • Trp53+/- • p53+/- • TGS-p53tm • p53 heterozygous |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Urinary bladder | Male |
100% (12 of 12 mice) |
27-28 weeks |
|
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11 |
| Urinary bladder | Male |
75% (9 of 12 mice) |
27-28 weeks |
|
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11 |
| Urinary bladder | Male |
23% (3 of 13 mice) |
27-28 weeks |
|
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11 |
| Urinary bladder | Male |
0% (0 of 13 mice) |
27-28 weeks |
|
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11 |
| Urinary bladder | Unspecified |
60% (6 of 10 mice) |
27-28 weeks |
|
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11 |