Model DetailsUrinary bladder squamous cell carcinoma

Model Name

Urinary bladder squamous cell carcinoma

Strain

B6.129S7-Trp53tm1Brd/+

Tumor Inducing Agent(s)

Chemical/Drug : N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)

Tumor Synonyms

squamous cell carcinoma of the urinary bladder  •  squamous cell carcinoma of the bladder  •  bladder carcinoma

Strain Synonyms

C57BL/6-Trp53tm1Bay/+  •  p53+/-  •  heterozygote p53 knockout  •  p53-deficient  •  p53(+/-)  •  TSG-p53(+/-)  •  Trp53+/-  •  p53+/-  •  TGS-p53tm  •  p53 heterozygous
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Urinary bladder Male

50%

(6 of 12 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Male

17%

(2 of 12 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
  • Pathology Reports
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Male

0%

(0 of 26 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Unspecified

20%

(2 of 10 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11