Model DetailsUrinary bladder dysplasia

Model Name

Urinary bladder dysplasia

Strain

B6.129S7-Trp53tm1Brd/+

Tumor Inducing Agent(s)

Chemical/Drug : N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)

Tumor Synonyms

bladder dysplasia  •  urinary bladder dysplasia

Strain Synonyms

C57BL/6-Trp53tm1Bay/+  •  p53+/-  •  heterozygote p53 knockout  •  p53-deficient  •  p53(+/-)  •  TSG-p53(+/-)  •  Trp53+/-  •  p53+/-  •  TGS-p53tm  •  p53 heterozygous
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Urinary bladder Male

100%

(12 of 12 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Male

100%

(12 of 12 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Male

69%

(9 of 13 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Genetics
Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Male

46%

(6 of 13 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11
Urinary bladder Unspecified

100%

(10 of 10 mice)
27-28 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

Ozaki K, Cancer Res 1998 Sep 1;58(17):3806-11