Model DetailsLiver hepatocellular carcinoma
Model Name |
Liver hepatocellular carcinoma | Strain |
B6;129-Stk11tm1Mmt/+ |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
hepatocellular carcinoma metastatic to the lung • liver carcinoma, hepatocellular • hepatocellular carcinoma |
Strain Synonyms |
Lkb1 heterozygote • Lkb1 +/- • Lkb1 (+/-) |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Liver | Male |
0% (0 of 7 mice) |
31-40 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Male |
29% (2 of 7 mice) |
41-50 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Male |
71% (5 of 7 mice) |
51-60 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Male |
75% (9 of 12 mice) |
>61 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Female |
0% (0 of 2 mice) |
31-40 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Female |
0% (0 of 3 mice) |
41-50 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Female |
33% (1 of 3 mice) |
51-60 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Female |
0% (0 of 2 mice) |
>61 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
| Liver | Unspecified |
observed |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 | |
| Lung | Unspecified |
observed |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 | |
| Liver | Male |
48% (16 of 33 mice) |
up to >61 weeks |
|
Nakau M, Cancer Res 2002 Aug 15;62(16):4549-53 |
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