Model DetailsPancreas adenocarcinoma - ductal
Model Name |
Pancreas adenocarcinoma - ductal | Strain |
[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
invasive pancreatic ductal adenocarcinoma liver metastasis • invasive pancreatic ductal adenocarcinoma • PDAC |
Strain Synonyms |
[not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)1Tuv Trp53tm2Tyj/+ • [not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+ • [not specified]-Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)6Tuv Trp53tm2Tyj/+ • Pdx1-Cre-GFP, LSL-KrasG12D/+, LSL-Trp53R172H/+ • KPC |
Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
---|---|---|---|---|---|
Pancreas | Unspecified |
observed |
10 months |
|
Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51 |
Liver | Unspecified |
65% (13 of 20 mice) |
|
Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51 | |
Pancreas | Unspecified |
77.78% (7 of 9 mice) |
100 days |
|
Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51 |