Model DetailsLiver tumor
Model Name |
Liver tumor | Strain |
[not specified]-Fahtm1Mgo Gt(ROSA)26Sortm2(sb11)Njen |
Tumor Inducing Agent(s) |
Chemical/Drug, Genetic Modification : Sleeping Beauty transposon expressing short hairpin against Trp53 and GFP (pT2/shp53) • Sleeping Beauty transposon expressing Nat10, Fah, firefly luciferase, and GFP (pT2/GD-Nat10) • nitisinone (NTBC) |
Tumor Synonym |
liver tumor |
Strain Synonyms |
Fah/SB11 • Fah-/-; Rosa26-SB11Tg/WT • Fah-/- Rosa26-SB11 |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Liver | Male |
91% (10 of 11 mice) |
182 days post injection |
|
Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588 |
| Liver | Female |
50% (7 of 14 mice) |
183 days post injection |
|
Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588 |