Model DetailsLiver tumor

Model Name

 Liver tumor

Strain
[not specified]-Fahtm1Mgo Gt(ROSA)26Sortm2(sb11)Njen

Tumor Inducing Agent(s)

 Chemical/Drug, Genetic Modification : Sleeping Beauty transposon expressing short hairpin against Trp53 and GFP (pT2/shp53)  •  Sleeping Beauty transposon expressing PrkacaL206R, Fah, firefly luciferase, and GFP (pT2/GD/PrkacaL206R)  •  nitisinone (NTBC)

Tumor Synonym

 liver tumor

Strain Synonyms

 Fah/SB11  •  Fah-/-; Rosa26-SB11Tg/WT  •  Fah-/- Rosa26-SB11
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Liver Mixed Population

31%

(8 of 26 mice) 		181-182 days post injection
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    120 days post injection

 Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588