Model DetailsLiver hepatocellular adenoma
Model Name |
Liver hepatocellular adenoma | Strain |
[not specified]-Fahtm1Mgo Gt(ROSA)26Sortm2(sb11)Njen |
Tumor Inducing Agent(s) |
Chemical/Drug, Genetic Modification : Sleeping Beauty transposon expressing short hairpin against Trp53 and GFP (pT2/shp53) • Sleeping Beauty transposon expressing Fah, firefly luciferase, and GFP (pkT2/GD-GFP) • nitisinone (NTBC) |
Tumor Synonyms |
hepatocellular adenoma • well-differentiated hepatocellular neoplasm |
Strain Synonyms |
Fah/SB11 • Fah-/-; Rosa26-SB11Tg/WT • Fah-/- Rosa26-SB11 |
Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
---|---|---|---|---|---|
Liver | Female |
14% (3 of 21 mice) |
183 days post injection |
|
Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588 |
Liver | Mixed Population |
7% (3 of 42 mice) |
183 days post injection |
|
Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588 |