Model DetailsProstate gland prostatic intraepithelial neoplasia - high grade (HGPIN)

Model Name

 Prostate gland prostatic intraepithelial neoplasia - high grade (HGPIN)

Strain
[not specified]-Brca2tm1Brn Tg(Pbsn-cre)4Prb Trp53tm1Brn

Tumor Inducing Agent(s)

 None (spontaneous)

Tumor Synonyms

 high-grade prostate intraepithelial neoplasia  •  prostate HG PIN

Strain Synonyms

 Brca2F/F;Trp53F/F;PBCre4  •  Brca2;Trp53 homozygous mutant
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Prostate gland Male

84%

(27 of 32 mice) 		15-19 months
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    12 months

  • Pathology Reports
Francis JC, PLoS Genet 2010;6(6):e1000995