Model DetailsProstate gland adenocarcinoma

Model Name

 Prostate gland adenocarcinoma

Strain
STOCK Krastm4Tyj/+ Nkx3-1tm4(cre/ERT2)Mms/+ Ptentm1Hwu

Tumor Inducing Agent(s)

 Genetic Modification : tamoxifen (for inducing expression from mutant alleles)

Tumor Synonyms

 prostate adenocarcinoma  •  prostate tumor  •  prostate carcinoma

Strain Synonyms

 Nkx3.1CreERT2/+; Ptenflox/flox; KrasG12D/+  •  Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+  •  NPK  •  Nkx3.1CreERT2/+; Ptenflox/flox; Kras12D/+  •  Nkx3.1CE2/+; Ptenf/f; Kras12D/+
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Prostate gland Male

~72

 4-7 months
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    3 months

  • Pathology Reports
  • Gene Expression Data
 Aytes A, Proc Natl Acad Sci U S A 2013 Sep 10;110(37):E3506-15