Strain SummaryFVB/N

Strain Name

 FVB/N

Strain Type(s)

 inbred

Strain Synonym(s)

 albino FVB/N  •  control  •  control FVB  •  FVB  •  FVB/n  •  FVB nontransgenic  •  N/E2  •  non-transgenic  •  nontransgenic FVB  •  nontransgenic FVB/N  •  wild type  •  wild-type  •  wild-type FVB  •  wild-type FVB/N

Strain Links

 • Festing's List of Inbred Strains

Models

64 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Cortex tumor Adrenal gland - Cortex ovariectomy

0

References: Bielinska M, Endocrinology 2003 Sep;144(9):4123-33

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Esophagus dysplasia Esophagus

0

References: Mueller A, Cancer Res 1997 Dec 15;57(24):5542-9   ⋅   Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Forestomach dysplasia Forestomach

0

References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Liver normal tissue (control) Liver

not applicable

References: Shachaf CM, Nature 2004 Oct 28;431(7012):1112-7

Liver tumor Liver diethylnitrosamine (DEN)

observed

References: Kuklin AI, Mol Cancer 2004 Jun 2;3(1):17

Lung - Alveolus hyperplasia Lung - Alveolus doxycycline

0

References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206

Lung - Alveolus hyperplasia - focal Lung - Alveolus

0

References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206

Lung adenocarcinoma Lung

0 - 6.45

References: Duan W, Oncogene 2002 Nov 7;21(51):7831-8

Lung carcinoma Lung

29

References: Shafarenko M, Carcinogenesis 1997 Jul;18(7):1423-6

Lung hyperplasia - focal Lung doxycycline

0

References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206

Lung hyperplasia - focal Lung

0

References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206

Lung tumor Lung Adenovirus - recombinant, expressing Cre recombinase

0

References: Meuwissen R, Oncogene 2001 Oct 4;20(45):6551-8

Lung tumor Lung doxycycline

0

References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206

Lung tumor Lung

0

References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206

Mammary gland adenoacanthoma Mammary gland pituitary isograft   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Li B, Oncogene 1998 Feb 26;16(8):997-1007

Mammary gland adenocarcinoma Mammary gland pituitary isograft   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Li B, Oncogene 1998 Feb 26;16(8):997-1007

Sites of Metastasis: Lung
Mammary gland foci Mammary gland

0

References: Pravtcheva DD, J Exp Zool 1998 May 1;281(1):43-57

Mammary gland hyperplasia Mammary gland

0 - observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Gallego MI, Oncogene 2003 Nov 20;22(52):8498-508   ⋅   Rudolph-Owen LA, Cancer Res 1998 Dec 1;58(23):5500-6

Mammary gland hyperplasia - alveolar Mammary gland

0

References: Pravtcheva DD, J Exp Zool 1998 May 1;281(1):43-57

Mammary gland metaplasia - squamous Mammary gland pituitary isograft   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Li B, Oncogene 1998 Feb 26;16(8):997-1007

Mammary gland tumor Mammary gland

0

0

0

References: Gallahan D, Cancer Res 1996 Apr 15;56(8):1775-85   ⋅   Liu S, Cancer Cell 2009 Jun 2;15(6):539-50   ⋅   Maroulakou IG, Proc Natl Acad Sci U S A 1994 Nov 8;91(23):11236-40   ⋅   Pravtcheva DD, J Exp Zool 1998 May 1;281(1):43-57   ⋅   Smith GH, Am J Pathol 1995 Oct;147(4):1081-96   ⋅   Takayama H, Proc Natl Acad Sci U S A 1997 Jan 21;94(2):701-6

Mammary gland tumor Mammary gland pituitary isograft   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

77.0 - 85.0

References: Li B, Oncogene 1998 Feb 26;16(8):997-1007

Mesodermal cell/mesoblast sarcoma - pleomorphic - undifferentiated Mesodermal cell/mesoblast Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Mesodermal cell/mesoblast sarcoma - spindle cell Skin

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Mesodermal cell/mesoblast sarcoma - spindle cell Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Mesodermal cell/mesoblast sarcoma - spindle cell Skin retinoic acid (RA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Mesodermal cell/mesoblast sarcoma - spindle cell Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)   ⋅   retinoic acid (RA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Mesodermal cell/mesoblast sarcoma - spindle cell Skin wounding

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Muscle - Smooth leiomyosarcoma Muscle - Smooth Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

0

0

References: Takayama H, Proc Natl Acad Sci U S A 1997 Jan 21;94(2):701-6

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Nose - Nasal cavity - Nasal gland hyperplasia Nose - Nasal cavity - Nasal gland

0

References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55

Prostate gland tumor Prostate gland

0

References: Maroulakou IG, Proc Natl Acad Sci U S A 1994 Nov 8;91(23):11236-40

Skin - Dorsal region papilloma Skin - Dorsal region 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   dimethylbenzanthracene (DMBA)

100

References: Ridd K, Carcinogenesis 2006 Aug;27(8):1556-66

Skin - Dorsal region papilloma Skin - Dorsal region 12-O-tetradecanoylphorbol-13-acetate (TPA)

0

References: Ridd K, Carcinogenesis 2006 Aug;27(8):1556-66

Skin - Ear squamous cell carcinoma Skin - Ear ear tag

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Skin - Melanocyte melanoma Skin - Melanocyte

0

References: Otsuka T, Cancer Res 1998 Nov 15;58(22):5157-67

Skin - Melanocyte melanoma - amelanotic Skin - Melanocyte

0

0

References: Takayama H, Proc Natl Acad Sci U S A 1997 Jan 21;94(2):701-6

Skin carcinoma Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Woodworth CD, Carcinogenesis 2004 Sep;25(9):1771-8

Skin dermatofibroma Skin Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Skin hyperplasia Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)

observed

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin papilloma Skin

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin papilloma Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin papilloma Skin retinoic acid (RA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin papilloma Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)   ⋅   retinoic acid (RA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin papilloma Skin wounding

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin papilloma Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Woodworth CD, Carcinogenesis 2004 Sep;25(9):1771-8

Skin squamous cell carcinoma Skin

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin squamous cell carcinoma Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin squamous cell carcinoma Skin retinoic acid (RA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin squamous cell carcinoma Skin phorbol 12-myristate 13-acetate (phorbol ester) (PMA)   ⋅   retinoic acid (RA)

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Skin squamous cell carcinoma Skin wounding

0

References: Leder A, Proc Natl Acad Sci U S A 1990 Dec;87(23):9178-82

Stomach lesion Stomach

0

References: Syder AJ, Proc Natl Acad Sci U S A 2004 Mar 30;101(13):4471-6

Subcutis tumor Subcutis Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Subcutis tumor Subcutis Ad5-CMV-LacZ (AdCMVLacZ)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Thymus hyperplasia Thymus

100

References: Scheijen B, J Biol Chem 2004 Mar 12;279(11):10476-83

Tongue dysplasia Tongue

0

References: Mueller A, Cancer Res 1997 Dec 15;57(24):5542-9   ⋅   Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Urinary bladder tumor Urinary bladder

0

References: Zhang ZT, Cancer Res 1999 Jul 15;59(14):3512-7

Uterus - Cervix cervical intraepithelial neoplasia (CIN) Uterus - Cervix 17beta-estradiol (E2)

0

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Uterus - Cervix squamous cell carcinoma Uterus - Cervix 17beta-estradiol (E2)

0

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

(Unspecified organ) angiosarcoma (Unspecified organ) Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

(Unspecified organ) tumor (Unspecified organ)

0

References: Jimenez M, Cancer Res 2004 Sep 1;64(17):6041-9