Model DetailsLeukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma
Model Name |
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Strain |
(C57BL/6 x C3H)F1 |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
histiocytic sarcoma • hemolymphoreticular neoplasm |
Strain Synonyms |
B6C3F1 • (C57BL/6xC3H) • F1-hybrid B6C3F1 • B6C3F1 • hybrid B6C3F1 • B6C3F1 (C3H x C57B16) • B6C3F1 hybrid |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
0.3% |
|
Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 | |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
1% |
|
Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6 | |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
6% (3 of 50 mice) |
103 weeks |
|
Fred C, Cancer Res 2008 Oct 1;68(19):8014-21 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
3.5% (7 of 200 mice) |
|
Chandra M, Toxicol Lett 1992 Jan;60(1):91-8 | |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
5.5% (11 of 200 mice) |
|
Chandra M, Toxicol Lett 1992 Jan;60(1):91-8 | |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
0.5% (7 of 1355 mice) |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
0% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
4% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
1.0% (11 of 1100 mice) |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
0% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Male |
6% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
1.4% (19 of 1353 mice) |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
0% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
4% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
3.2% (35 of 1092 mice) |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
0% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |
| Leukocyte - Monocyte - Macrophage - Histiocyte | Female |
10% |
2 years |
|
Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41 |