PDX Model DetailsTM00312

Request information on the availability of this model.

PDX Model Summary

Model Details
Model ID (Previous ID)
TM00312 (PA0252F)
Initial Diagnosis
Pancreatic ductal adenocarcinoma
Final Diagnosis
Pancreatic ductal adenocarcinoma
Stage/Grade
Not Specified /
Primary Site
Pancreas
Sample Site
Pancreas
Tumor Type
Primary Malignancy

Patient
Sex
Male
Age (at time of tissue collection)
60
Race/Ethnicity
White / Not Hispanic or Latino
Treatment Naïve?
Yes
Current Smoker/Former Smoker
No / No

Engraftment
Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Surgical resection (fragment)
Engraftment Site
no data

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

no expression plots

Gene CNV

no CNV data

CNV Plots

no CNV plots

Tumor Mutation Burden

 no data

Microsatellite Instability

 no data

Gene Fusion

 no data

Model Characterization

Histology

 Summary:
P0 pathology consistent with mucinous adenocarcinoma.
Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P0 tumor F1882 for PDX model TM00312 stained for H&E.
P0 tumor F1882 for PDX model TM00312 stained for AE1AE3. Staining was positive.

P0 tumor F1882 for PDX model TM00312 stained for CD45. Staining was negative.

Dosing Studies

 no data

Circos Plots

 no data