PDX Model DetailsTM00047

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PDX Model Summary

Model Details
Model ID (Previous ID)
TM00047 (BN0338F)
Initial Diagnosis
Brain glioblastoma multiforme
Final Diagnosis
Adult glioblastoma multiforme
Stage/Grade
Not Specified / Grade:IV
Model Status
Active Available - QC Complete
Primary Site
Brain
Sample Site
Brain
Tumor Type
Primary Malignancy

Patient
Sex
Male
Age (at time of tissue collection)
67
Race/Ethnicity
White / Not Reported
Treatment Naïve?
Yes
Current Smoker/Former Smoker
No / No

Engraftment
Host Strain
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
(aka NSG or NOD Scid gamma)
Sample Type
Not Specified
Engraftment Site
no data

Molecular Data (Engrafted Tumor)

Variants

Gene Expression

 Data Links:

Sample:BN0338F1462P0 from passage:P0 Platform:hg10st Derived Data  Raw data 1 


Sample:BN0338F1466P0 from passage:P0 Platform:hu133 Derived Data  Raw data 1 


Platforms: hg10st, hu133

Gene CNV

no CNV data

CNV Plots

no CNV plots

Tumor Mutation Burden

 no data

Microsatellite Instability

 no data

Gene Fusion

 no data

Model Characterization

Histology

 Pathologist:
Dr. Regina Gandour-Edwards, University of California, Davis

P0 tumor F1462 for PDX model TM00047 stained for H&E.
P0 tumor F1462 for PDX model TM00047 stained for GFAP. Staining was positive.

P1 tumor F1462 ID082 for PDX model TM00047 stained for H&E.
P1 tumor F1462 ID082 for PDX model TM00047 stained for GFAP. Staining was positive.

P1 tumor F1462 ID082 for PDX model TM00047 stained for CD45. Staining was negative.

Dosing Studies

 no data

Circos Plots

Circos plot for P0 tumor #1462 for PDX model TM00047 (aka, BN0338F)
Circos plot for P0 tumor #1466 for PDX model TM00047 (aka, BN0388F)