Reference SummaryHeston WE, J Natl Cancer Inst 1964 Jan;32():237-51

Title

Strain DD, a new high mammary tumor strain, and comparison of DD with strain C3H

Authors

Heston WE; Vlahakis G; Tsubura Y

Journal

J Natl Cancer Inst

Volume

32

Issue

Year

1964

Pages

237-51

Abstract

Links

J:24690 – MGI References
14114970 – National Library of Medicine/PubMed

Strain Notes

Strain Note
C3Hf/He Mice were NOT carriers of infectious MMTV.
C3Hf/HefC3H/He Mice were carriers of infectious MMTV.
C3Hf/HefDD/He Mice were carriers of infectious MMTV.
C3H/He Mice were carriers of infectious MMTV.
C3H/HefDD/He Mice were carriers of infectious MMTV.
DD/He Mice were carriers of infectious MMTV.
DD/HefC3H/He Mice were carriers of infectious MMTV.

Models

Strain Model Name Treatment Agent(s) Organ Affected Frequency Model Details
C3Hf/He Blood vessel hemangioendothelioma Blood vessel

2.5

DD/He Blood vessel hemangioendothelioma Blood vessel

0.4

C3Hf/HefDD/He Blood vessel hemangioendothelioma Blood vessel

1.0

C3H/HefDD/He Blood vessel hemangioendothelioma Blood vessel

3.9

C3H/He Blood vessel hemangioendothelioma Blood vessel

0.9

C3Hf/He Blood vessel hemangioma Blood vessel

0.2

C3Hf/He Bone osteosarcoma Bone

0.4

C3Hf/He Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

2.8

C3Hf/HefDD/He Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

1.0

C3Hf/HefDD/He Eye - Harderian gland tumor Eye - Harderian gland

1.0

C3Hf/He Kidney carcinoma Kidney

0.2

DD/He Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Eye

0.4

C3Hf/He Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

0.2

C3H/HefDD/He Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

1.0

C3Hf/He Leukocyte lymphoma Leukocyte

0.4

C3H/HefDD/He Leukocyte lymphoma Leukocyte

1.0

C3Hf/He Liver hepatoma Liver

25

C3Hf/HefC3H/He Liver hepatoma Liver

5

C3Hf/HefDD/He Liver hepatoma Liver

41

C3H/HefDD/He Liver hepatoma Liver

39

C3H/He Liver hepatoma Liver

0

C3Hf/He Lung tumor Lung

5.5

C3Hf/HefC3H/He Lung tumor Lung

1

C3Hf/HefDD/He Lung tumor Lung

5.8

C3H/HefDD/He Lung tumor Lung

1.9

DD/HefC3H/He Lung tumor Lung

0.9

C3H/He Lung tumor Lung

0.9

DD/He Lung tumor Lung

2.9

C3Hf/He Mammary gland adenoacanthoma Mammary gland

9.6

DD/He Mammary gland adenoacanthoma
  • MMTV - mouse mammary tumor virus
Mammary gland

0.4

C3Hf/HefC3H/He Mammary gland adenoacanthoma
  • MMTV - mouse mammary tumor virus
Mammary gland

1

C3Hf/HefC3H/He Mammary gland adenocarcinoma
  • MMTV - mouse mammary tumor virus
Mammary gland

96

C3Hf/HefDD/He Mammary gland adenocarcinoma
  • MMTV - mouse mammary tumor virus
Mammary gland

72

C3H/HefDD/He Mammary gland adenocarcinoma
  • MMTV - mouse mammary tumor virus
Mammary gland

77

DD/HefC3H/He Mammary gland adenocarcinoma
  • MMTV - mouse mammary tumor virus
Mammary gland

92

C3H/He Mammary gland adenocarcinoma
  • MMTV - mouse mammary tumor virus
Mammary gland

100

DD/He Mammary gland adenocarcinoma
  • MMTV - mouse mammary tumor virus
Mammary gland

75

C3Hf/He Mammary gland adenocarcinoma - type A Mammary gland

18

DD/He Mammary gland adenocarcinoma - type A
  • MMTV - mouse mammary tumor virus
Mammary gland

low

C3Hf/He Mammary gland adenocarcinoma - type B Mammary gland

19

DD/He Mammary gland adenocarcinoma - type B
  • MMTV - mouse mammary tumor virus
Mammary gland

very high

C3H/He Mammary gland tumor
  • MMTV - mouse mammary tumor virus
Mammary gland

99

C3Hf/He Mammary gland tumor Mammary gland

2 - 40

DD/He Mammary gland tumor
  • MMTV - mouse mammary tumor virus
Mammary gland

27 - 84

DD/He Mammary gland tumor - benign
  • MMTV - mouse mammary tumor virus
Mammary gland

0.8

(C3H x Y)F1 Mammary gland tumor - benign Mammary gland

observed

C3Hf/He Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

0.6

DD/HefC3H/He Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

0.9

C3Hf/He Ovary tumor Ovary

5.9

C3Hf/HefDD/He Ovary tumor Ovary

1.9

C3H/HefDD/He Ovary tumor Ovary

1.0

DD/He Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

1.0

DD/He Skin papilloma Skin

observed

C3Hf/He Uterus adenoma - fibroid Uterus

0.2

C3Hf/HefDD/He Uterus adenoma - fibroid Uterus

1.0

C3H/HefDD/He Uterus adenoma - fibroid Uterus

1.0

C3Hf/He (Unspecified organ) papilloma (Unspecified organ)

0.2

DD/He (Unspecified organ) papilloma (Unspecified organ)

4.9 - 7.5

C3Hf/HefDD/He (Unspecified organ) papilloma (Unspecified organ)

1.9

DD/HefC3H/He (Unspecified organ) papilloma (Unspecified organ)

2.7

C3Hf/He (Unspecified organ) squamous cell carcinoma (Unspecified organ)

0.8

DD/He (Unspecified organ) squamous cell carcinoma (Unspecified organ)

1.0

C3Hf/He (Unspecified organ) tumor (Unspecified organ)

3 - 3.4

DD/He (Unspecified organ) tumor (Unspecified organ)

0.8 - 2.0

C3Hf/HefDD/He (Unspecified organ) tumor (Unspecified organ)

2.9