Strain SummaryFVB/N-Tg(L2hD)#Aru

Strain Name

FVB/N-Tg(L2hD)#Aru

Strain Type(s)

transgenic

Strain Synonym(s)

cyclin D1  •  EBV ED-L2-cyclin D1  •  EBV ED-L2 human cyclin D1  •  Epstein-Barr virus ED-L2 human cyclin D1  •  FVB/N-TgN(CCND1)#  •  FVB/N-TgN(L2hD)#Aru  •  human cyclin D1  •  L2hD

Description

(# - founder number not specified) Three founder lines transmitted the transgene (#'s 3, 6, and 8) but the reference did not distinguish between these lines. These mice carry a transgene containing human CCND1 under the control of the EBV ED-L2 promoter.

Strain Genetics

Tg(L2hD)#Aru

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Esophagus carcinoma Esophagus

0

References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Esophagus dysplasia Esophagus

100

References: Mueller A, Cancer Res 1997 Dec 15;57(24):5542-9   ⋅   Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Forestomach carcinoma Forestomach

0

References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Forestomach dysplasia Forestomach

100

References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Tongue carcinoma Tongue

0

References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90

Tongue dysplasia Tongue

100

References: Mueller A, Cancer Res 1997 Dec 15;57(24):5542-9   ⋅   Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90