Strain SummaryFVB/N-Tg(L2hD)#Aru
Strain Name |
FVB/N-Tg(L2hD)#Aru |
Strain Type(s) |
transgenic |
Strain Synonym(s) |
cyclin D1 • EBV ED-L2-cyclin D1 • EBV ED-L2 human cyclin D1 • Epstein-Barr virus ED-L2 human cyclin D1 • FVB/N-TgN(CCND1)# • FVB/N-TgN(L2hD)#Aru • human cyclin D1 • L2hD |
Description |
(# - founder number not specified) Three founder lines transmitted the transgene (#'s 3, 6, and 8) but the reference did not distinguish between these lines. These mice carry a transgene containing human CCND1 under the control of the EBV ED-L2 promoter. |
Strain Genetics |
Tg(L2hD)#Aru |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Esophagus carcinoma | Esophagus |
0 |
References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90 |
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Esophagus dysplasia | Esophagus |
100 |
References: Mueller A, Cancer Res 1997 Dec 15;57(24):5542-9 ⋅ Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90 |
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Forestomach carcinoma | Forestomach |
0 |
References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90 |
|||||
Forestomach dysplasia | Forestomach |
100 |
References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90 |
|||||
Tongue carcinoma | Tongue |
0 |
References: Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90 |
|||||
Tongue dysplasia | Tongue |
100 |
References: Mueller A, Cancer Res 1997 Dec 15;57(24):5542-9 ⋅ Nakagawa H, Oncogene 1997 Mar 13;14(10):1185-90 |