Strain SummaryFVB/N-Tg(Trp53R172H)8512Jmr

Strain Name	FVB/N-Tg(Trp53R172H)8512Jmr
Strain Type(s)	transgenic
Strain Synonym(s)	172Arg-to-His p53 mutant • FVB/N-TgN(Trp53R172H)8512Jmr • line #8512 • line 8512 • line 8512 WAP-p53-172H • p53-172H • p53172R-H • p53^Arg-His • TG^d • WAP p53 172^R-H
Strain Genetics	List all models in MMHCdb carrying the Tg(Trp53R172H)8512Jmr allele Tg(Trp53R172H)8512Jmr

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Mammary gland adenocarcinoma - type B	Mammary gland	pituitary isograft ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)	observed				References: Li B, Oncogene 1998 Feb 26;16(8):997-1007
Mammary gland adenoma	Mammary gland	pituitary isograft ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)	observed				References: Li B, Oncogene 1998 Feb 26;16(8):997-1007
Mammary gland tumor	Mammary gland		0 - 20				References: Li B, Mol Cell Biol 1997 Jun;17(6):3155-63 ⋅ Li B, Oncogene 1998 Feb 26;16(8):997-1007
Mammary gland tumor	Mammary gland	pituitary isograft ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)	100				References: Li B, Oncogene 1998 Feb 26;16(8):997-1007

Models