Strain SummaryCD-1.129S2-Ptch1tm1Zim/+

Strain Name

 CD-1.129S2-Ptch1tm1Zim/+

Strain Type(s)

 congenic  •  targeted mutation (knockout)

Strain Synonym(s)

 CD1,129-Ptchtm1Zim/+  •  CD1;129S2-Ptchtm1Zim/+  •  CD1 Ptc1+/-  •  CD1 Ptch+/ptch tm67neo  •  CD1 ptch+/ptchtm neo67  •  Ptc1 heterozygote  •  ptc1+/-  •  Ptc1+/-  •  Ptchneo67/+  •  ptcneo67/+

Description

 Heterozygous mice. The genetic background of this strain is a mixture of CD-1 and 129S2/SvPas.

Strain Genetics

 Ptch1tm1Zim / Ptch1+

Models

10 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Undifferentiated cell medulloblastoma CNS - Brain - Undifferentiated cell X-radiation

0 - 51

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

CNS - Brain - Undifferentiated cell medulloblastoma CNS - Brain - Undifferentiated cell

6.7 - 7.7

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

Leukocyte lymphoma Thymus X-radiation

2.4 - 25

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

Leukocyte lymphoma Thymus

0 - 3.3

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast X-radiation

7.8 - 37

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3.8 - 40

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

Muscle - Striated - Skeletal - Abdomen rhabdomyosarcoma Muscle - Striated - Skeletal - Abdomen

observed

References: Pathbase web site, University of Cambridge, MGI Direct Data Submission 2009;():

3 pathology image(s)
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

8.5 - 15

References: Calzada-Wack J, Carcinogenesis 2002 May;23(5):727-33   ⋅   Hahn H, Nat Med 1998 May;4(5):619-22

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell X-radiation

0 - 15

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4

(Unspecified organ) tumor (Unspecified organ)

0 - 7.7

References: Pazzaglia S, Oncogene 2002 Oct 24;21(49):7580-4