Strain SummaryB6;129S3-Nkx3-1tm1Mms/+
Strain Name |
B6;129S3-Nkx3-1tm1Mms/+ |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
C57Bl/6J/129/SvImJ Nkx3.1+/- • Nkx3.1+/- • Nkx3.1+/- |
Description |
Mice heterozygous for a targeted mutation of the Nkx3-1 gene. The genetic background was a mixture of C57BL/6J and 129S3/SvImJ. |
Strain Genetics |
Nkx3-1tm1Mms / Nkx3-1+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Prostate gland - Epithelial cell hyperplasia | Prostate gland - Epithelial cell |
observed - 36 |
References: Bhatia-Gaur R, Genes Dev 1999 Apr 15;13(8):966-77 ⋅ Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004 |
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Prostate gland - Epithelial cell prostatic intraepithelial neoplasia (PIN) | Prostate gland - Epithelial cell |
0 - 43 |
References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004 |