Strain SummaryB6;129S3-Nkx3-1^tm1Mms

Strain Name	B6;129S3-Nkx3-1^tm1Mms
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	C57Bl/6J/129/SvImJ Nkx3.1^-/- • Nkx3.1^-/- • Nkx3.1^-/-
Description	Mice homozygous for a targeted mutation of the Nkx3-1 gene. The genetic background was a mixture of C57BL/6J and 129S3/SvImJ.
Strain Genetics	List all models in MMHCdb carrying the Nkx3-1^tm1Mms allele Nkx3-1^tm1Mms / Nkx3-1^tm1Mms

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Prostate gland - Epithelial cell carcinoma	Prostate gland - Epithelial cell			0			References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004
Prostate gland - Epithelial cell hyperplasia	Prostate gland - Epithelial cell			0 - 38			References: Bhatia-Gaur R, Genes Dev 1999 Apr 15;13(8):966-77 ⋅ Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004
Prostate gland - Epithelial cell prostatic intraepithelial neoplasia (PIN)	Prostate gland - Epithelial cell			0 - 69			References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004

Models