Strain SummarySTOCK Cdkn2atm1Rdp/+ Tg(Tyr-HRAS)60Lc
Strain Name |
STOCK Cdkn2atm1Rdp/+ Tg(Tyr-HRAS)60Lc |
Strain Type(s) |
targeted mutation (knockout) • transgenic |
Strain Synonym(s) |
ink4a+/- transgenic • tyr-ras ink4a+/- • STOCK Tg(Tyr-HRAS)60Lc Cdkn2atm1Rdp/+ • TR60 ink4a+/- |
Description |
Mice were heterozygous for the Cdkn2a allele and carried the transgene. This STOCK genetic background was a mixture of C57BL/6J, CBA/J, "129/Sv" (substrain unspecified), and SJL/J. |
Strain Genetics |
Cdkn2atm1Rdp / Cdkn2a+ |
Tg(Tyr-HRAS)60Lc |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Skin - Melanocyte melanoma | Skin - Melanocyte |
4 |
References: Chin L, Genes Dev 1997 Nov 1;11(21):2822-34 |