Strain SummarySTOCK Cdkn2atm1Rdp/+ Tg(Tyr-HRAS)60Lc

Strain Name

STOCK Cdkn2atm1Rdp/+ Tg(Tyr-HRAS)60Lc

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

ink4a+/- transgenic  •  tyr-ras ink4a+/-  •  STOCK Tg(Tyr-HRAS)60Lc Cdkn2atm1Rdp/+  •  TR60 ink4a+/-

Description

Mice were heterozygous for the Cdkn2a allele and carried the transgene. This STOCK genetic background was a mixture of C57BL/6J, CBA/J, "129/Sv" (substrain unspecified), and SJL/J.

Strain Genetics

Cdkn2atm1Rdp / Cdkn2a+
Tg(Tyr-HRAS)60Lc

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin - Melanocyte melanoma Skin - Melanocyte

4

References: Chin L, Genes Dev 1997 Nov 1;11(21):2822-34