Strain SummaryB6AF1-Trp53^tm1Brd/+

Strain Name	B6AF1-Trp53^tm1Brd/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	TSG-p53 • (TSG-p53 X A/J)F₁ p53^wt/null
Description	Heterozygous mice. B6.129S7-Trp53^tm1Brd/+ mice (generated using ES cells from 129S7/SvEvBrd-Hprt⁺ mice and backcrossed to C57BL/6J mice) were crossed one time to A/J mice.
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Brd allele Trp53^tm1Brd / Trp53⁺

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Lung adenoma	Lung				11		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7
Lung adenoma	Lung	N-methyl-N-nitrosourea (MNU)			100		References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7

Models