Strain SummaryFVBAF1-Tg(Trp53A135V)3Tgd
Strain Name |
FVBAF1-Tg(Trp53A135V)3Tgd |
Strain Type(s) |
hybrid • transgenic |
Strain Synonym(s) |
FVBAF1-TgN(Trp53A135V)3Tgd • (FVB/N x A/J)F1-TgN(Trp53A135V)3Tgd • (FVB/N x A/J)F1-TgN(UL53)3Tgd • UL53-3 • (UL53-3 x A/J)F1 p53Val135/wt |
Description |
Hemizygous mice. FVB/N-Tg(Trp53A135V)3Tgd were crossed once to A/J mice. |
Strain Genetics |
Tg(Trp53A135V)3Tgd |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Lung adenoma | Lung |
0 - 5.0 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
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Lung adenoma | Lung | N-methyl-N-nitrosourea (MNU) |
100 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
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Lung adenoma | Lung | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) |
100 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
||||
Lung adenoma | Lung | benzo[a]pyrene (BP) (BaP) (B[a]P) |
100 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
||||
Lung adenoma | Lung | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ dexamethasone (DEX) ⋅ myo-inositol |
95 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
||||
Lung adenoma | Lung | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ green tea |
100 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
||||
Lung adenoma | Lung | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ Taxol (paclitaxel) |
100 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |
||||
Lung adenoma | Lung | 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) ⋅ Adriamycin |
100 |
References: Zhang Z, Cancer Res 2000 Feb 15;60(4):901-7 |