Strain SummaryCD-1-Tg(MtTGFA)42Lmb

Strain Name

 CD-1-Tg(MtTGFA)42Lmb

Strain Type(s)

 transgenic

Strain Synonym(s)

 CD-1-derived MT42  •  CD1-derived TGF-α-transgenic  •  CD-1-TgN(MtTGFA)42Lmb  •  line MT42  •  MT42  •  MT42 TGF-α  •  MT-TGF-α  •  MT-TGFα  •  TGF-α  •  TGF-α transgenic  •  TGF-α transgenic line MT42

Strain Genetics

 Tg(MtTGFA)42Lmb

Models

34 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Liver - Hepatocyte foci Liver - Hepatocyte ZnSO4

0 - 10

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver - Hepatocyte foci Liver - Hepatocyte ZnSO4   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver - Hepatocyte foci Liver - Hepatocyte ZnSO4   ⋅   phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver - Hepatocyte foci Liver - Hepatocyte ZnSO4   ⋅   phenobarbital (PB)

0 - 67

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver adenoma - clear cell Liver

observed

observed

References: Jhappan C, Cell 1990 Jun 15;61(6):1137-46

Liver dysplasia Liver (see notes)

observed

References: Jhappan C, Cell 1990 Jun 15;61(6):1137-46

Liver dysplasia Liver

observed

References: Jhappan C, Cell 1990 Jun 15;61(6):1137-46

Liver hepatocellular adenoma Liver

observed

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular adenoma Liver ZnSO4   ⋅   castration

10

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular adenoma Liver (see notes)

very low

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular adenoma Liver ZnSO4

0

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver hepatocellular adenoma Liver ZnSO4   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

0 - 100

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver hepatocellular adenoma Liver ZnSO4   ⋅   phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed - 80

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver hepatocellular adenoma Liver ZnSO4   ⋅   phenobarbital (PB)

0 - 33

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver hepatocellular carcinoma Liver

observed

observed

References: Jhappan C, Cell 1990 Jun 15;61(6):1137-46   ⋅   Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular carcinoma Liver (see notes)

0

65

References: Jhappan C, Cell 1990 Jun 15;61(6):1137-46   ⋅   Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular carcinoma Liver ZnSO4

0

0 - 43

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7   ⋅   Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver hepatocellular carcinoma Liver ZnSO4   ⋅   castration

0

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular carcinoma Liver ZnSO4   ⋅   testosterone   ⋅   ovariectomy

50

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular carcinoma Liver ZnSO4   ⋅   ovariectomy

14

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver hepatocellular carcinoma Liver ZnSO4   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

0 - 100

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver hepatocellular carcinoma Liver ZnSO4   ⋅   phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

0 - 100

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Sites of Metastasis: Lung
Liver hepatocellular carcinoma Liver ZnSO4   ⋅   phenobarbital (PB)

0 - 33

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver tumor Liver (see notes)

very low

74

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver tumor Liver ZnSO4

11

0 - 86

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7   ⋅   Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver tumor Liver

62

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver tumor Liver ZnSO4   ⋅   castration

10

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver tumor Liver ZnSO4   ⋅   ovariectomy

57

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver tumor Liver ZnSO4   ⋅   testosterone   ⋅   ovariectomy

67

References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver tumor Liver ZnSO4   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

100

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver tumor Liver ZnSO4   ⋅   phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

90

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Liver tumor Liver ZnSO4   ⋅   phenobarbital (PB)

17

References: Tamano S, Carcinogenesis 1994 Sep;15(9):1791-8

Mammary gland tumor Mammary gland

observed

References: Smith GH, Am J Pathol 1995 Oct;147(4):1081-96

Pancreas - Duct metaplasia Pancreas - Duct ZnCl2

observed

References: Jhappan C, Cell 1990 Jun 15;61(6):1137-46