Strain SummaryB6;CD-1-Tg(MtTGFA)42Lmb

Strain Name	B6;CD-1-Tg(MtTGFA)42Lmb
Strain Type(s)	transgenic
Strain Synonym(s)	B6;CD-1-TgN(MtTGFA)42Lmb • C57BL/6 X CD1 MT42 • MT-TGFα • MT-TGFα Ink4a/Arf^+/+ • MT42 • MT42 CD1/C57BL/6 • MT42 X C57BL/6 • TGFα
Description	The genetic background of these mice was a mixture of C57BL/6 and CD-1.
Strain Genetics	Trp53⁺ / Trp53⁺
	Cdkn2a⁺ / Cdkn2a⁺
	List all models in MMHCdb carrying the Tg(MtTGFA)42Lmb allele Tg(MtTGFA)42Lmb

Models
5 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Liver hepatocellular carcinoma	Liver					observed - 67	References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43 ⋅ Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7
Liver tumor	Liver					83	References: Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7
Pancreas metaplasia - tubular	Pancreas					100	References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43
Pancreas tumor	Pancreas					0	References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43
(Unspecified organ) tumor	(Unspecified organ)					0	References: Bardeesy N, Mol Cell Biol 2002 Jan;22(2):635-43

Models