Strain SummaryCD-1;129-Cdk4^tm1.1Bbd/+

Strain Name	CD-1;129-Cdk4^tm1.1Bbd/+
Strain Type(s)	targeted mutation (knock-in)
Strain Synonym(s)	Cdk4^+/R24C • mixed 129/SvJ X CD-1 Cdk4^+/R24C
Description	Heterozygous mice. The genetic background of these mice was a mixture of 129X1/SvJ, 129S1/Sv, and outbred CD-1.
Strain Genetics	List all models in MMHCdb carrying the Cdk4^tm1.1Bbd allele Cdk4^tm1.1Bbd / Cdk4⁺

Models
4 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Skin - Melanocyte melanoma	Skin - Melanocyte	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				observed	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7
Skin lesion	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				very high	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7
Skin papilloma	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				very high	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7
(Unspecified organ) tumor	(Unspecified organ)					observed	References: Sotillo R, EMBO J 2001 Dec 3;20(23):6637-47

Models