Strain SummaryFVB.129S3-Nkx3-1tm1Mms/+

Strain Name

FVB.129S3-Nkx3-1tm1Mms/+

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

FVB/N Nkx3.1+/-  •  Nkx3.1+/-

Description

Mice heterozygous for a targeted mutation of Nkx3-1. Congenic animals were produced by 10 generations of sequential back-crosses.

Strain Genetics

Nkx3-1tm1Mms / Nkx3-1+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Prostate gland - Epithelial cell hyperplasia Prostate gland - Epithelial cell

42

References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004

Prostate gland - Epithelial cell prostatic intraepithelial neoplasia (PIN) Prostate gland - Epithelial cell

25

References: Kim MJ, Cancer Res 2002 Jun 1;62(11):2999-3004