Strain SummaryB6.Cg-Cdkn2a^tm1Rdp

Strain Name	B6.Cg-Cdkn2a^tm1Rdp
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	C57BL/6J INK4aΔ2,3 • INK4a-ARF null • p16^INK4a p19^ARF deficient
Description	Homozygous mice. This strain has been backcrossed to C57BL/6J. Mice carrying this mutation were originally generated using the WW6 ES cell line (75% 129/Sv, 20% C57BL/6J, 5% SJL).
Strain Genetics	List all models in MMHCdb carrying the Cdkn2a^tm1Rdp allele Cdkn2a^tm1Rdp / Cdkn2a^tm1Rdp

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Leukocyte lymphoma	Leukocyte	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				100	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7
Skin lesion	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				0	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7

Models