Strain SummaryAKR

Strain Name	AKR
Strain Type(s)	inbred
Strain Synonym(s)	Afb • Ak • Akm • RIL • R.I.L. • Rockefeller Institute Leukemia
Description	Substrain not specified.
Strain Links	• Festing's List of Inbred Strains
Strain Genetics	List all models in MMHCdb carrying the Thy1^a allele Thy1^a / Thy1^a

Models
18 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Bone osteoma	Bone		observed	observed			References: Furth J, J Gerontol 1946;1():46-54
Bone osteoma	Bone	thymectomy	observed	observed			References: Furth J, J Gerontol 1946;1():46-54
Bone osteosarcoma	Bone					observed	References: Franks LM, J Natl Cancer Inst 1973 Feb;50(2):431-8
Leukocyte - Lymphocyte leukemia - lymphocytic	Leukocyte - Lymphocyte		4 - 65	high - 57	84	66.0 - 91.0	References: Fekete E, Cancer Res 1954;14():445-47 ⋅ Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 ⋅ Staats J, Cancer Res 1985 Mar;45(3):945-77 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;(): ⋅ Staats J, Companion to Mouse News Lett No. 25 1961;():
Leukocyte - Lymphocyte leukemia - lymphocytic	Thymus		83	68		90	References: Staats J, Companion to Mouse News Lett No. 33 1965;():
Leukocyte - Lymphocyte lymphohematopoietic neoplasm	Leukocyte - Lymphocyte					high	References: Murphy ED, 1966;():521-62
Leukocyte leukemia	Leukocyte		80.0 - 100	70.0 - 80.0		high - 92.0	References: Duran-Reynals ML, J Natl Cancer Inst 1974 Mar;52(3):1001-3 ⋅ Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Furth J, J Gerontol 1946;1():46-54 ⋅ Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20 ⋅ Heston WE, 1963;():247-68 ⋅ International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;():
Leukocyte leukemia	Leukocyte	thymectomy	11	9			References: Furth J, J Gerontol 1946;1():46-54
Leukocyte leukemia	Leukocyte	mainstream cigarette smoke (MCS)	100				References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20
Leukocyte lymphoma	Leukocyte					observed	References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Liver - Hepatocyte preneoplastic lesion	Liver - Hepatocyte	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7
Liver carcinoma in situ	Liver	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7
Liver hepatocellular carcinoma - well-differentiated	Liver	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7
Liver hyperplasia	Liver	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Giri RK, Cancer Lett 1996 Dec 3;109(1-2):121-7
Lung tumor	Lung		0	1		1	References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831
Mammary gland adenocarcinoma	Mammary gland		0 - 1	0		1	References: Festing MFW, Mouse Genome 1996;94(3):523-677 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831
Thymus leukemia	Thymus					observed	References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Thymus lymphoma	Thymus					observed	References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105