Strain SummaryB6.Cg-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s
Strain Name |
B6.Cg-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s |
Strain Type(s) |
chemically induced mutation • congenic • spontaneous mutation • targeted mutation (knockout) |
Strain Synonym(s) |
B6.Cg(FVB)-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s/Mom1-s • B6.Cg(FVB)-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s • C57BL/6J ApcMin/+ Pla2g2a-/- Mdr1a/b-/- • Mdr1-deficient ApcMin/+ • Mdr1-deficient Min • Mdr1-/- ApcMin/+ • N6F1 ApcMin/+ Mdr1a/b-/- |
Description |
Homozygous for the Abcb1a, Abcb1b, & C57BL/6 derived Pla2g2aMom1-s alleles & heterozygous for ApcMin. The genetic background is congenic for C57BL/6J with contribitions from FVB and 129P2/OlaHsd. |
Strain Genetics |
ApcMin / Apc+ |
Abcb1btm1Bor / Abcb1btm1Bor | |
Pla2g2aMom1-s / Pla2g2aMom1-s | |
Abcb1atm1Bor / Abcb1atm1Bor |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine - Large Intestine - Colon polyp | Intestine - Large Intestine - Colon |
observed |
observed |
References: Yamada T, Cancer Res 2003 Mar 1;63(5):895-901 |
||||
Intestine - Small Intestine polyp | Intestine - Small Intestine |
observed |
observed |
References: Yamada T, Cancer Res 2003 Mar 1;63(5):895-901 |