Strain SummaryB6.Cg-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s

Strain Name

B6.Cg-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s

Strain Type(s)

chemically induced mutation  •  congenic  •  spontaneous mutation  •  targeted mutation (knockout)

Strain Synonym(s)

B6.Cg(FVB)-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s/Mom1-s  •  B6.Cg(FVB)-Abcb1atm1Bor Abcb1btm1Bor ApcMin/+ Pla2g2aMom1-s  •  C57BL/6J ApcMin/+ Pla2g2a-/- Mdr1a/b-/-  •  Mdr1-deficient ApcMin/+  •  Mdr1-deficient Min  •  Mdr1-/- ApcMin/+  •  N6F1 ApcMin/+ Mdr1a/b-/-

Description

Homozygous for the Abcb1a, Abcb1b, & C57BL/6 derived Pla2g2aMom1-s alleles & heterozygous for ApcMin. The genetic background is congenic for C57BL/6J with contribitions from FVB and 129P2/OlaHsd.

Strain Genetics

ApcMin / Apc+
Abcb1btm1Bor / Abcb1btm1Bor
Pla2g2aMom1-s / Pla2g2aMom1-s
Abcb1atm1Bor / Abcb1atm1Bor

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon

observed

observed

References: Yamada T, Cancer Res 2003 Mar 1;63(5):895-901

Intestine - Small Intestine polyp Intestine - Small Intestine

observed

observed

References: Yamada T, Cancer Res 2003 Mar 1;63(5):895-901