Strain SummaryB6.129S7-Trp53tm1Brd/+
Strain Name |
B6.129S7-Trp53tm1Brd/+ |
Strain Type(s) |
congenic • targeted mutation (knockout) |
Strain Synonym(s) |
B6.129-Trp53tm1Brd/+ • C57bl/6N12-Trp53 heterozygous (+/-) • C57BL/6TacfBR-[KO] p53 N5 heterozygous mice • C57Bl/6Tac-[KO]Trp53N5-T • heterozygous p53 knockout • p53+/- • p53(+/-) • p53+/- • p53-deficient • p53+/- • p53+/- Deficient |
Description |
Heterozygous mice. The genetic background of these mice is congenic for C57BL/6NTac with some contribution from 129S7/SvEvBrd-Hprt+. Mice were purchased from Taconic. |
Strain Genetics |
Trp53tm1Brd / Trp53+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Adrenal gland - Cortex adenoma | Adrenal gland - Cortex |
0 |
0 - 0.2 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Adrenal gland - Cortex adenoma | Adrenal gland - Cortex | phenacetin |
0 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla |
0 |
0.2 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla | Cyclosporin A |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Blood vessel hemangioma | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Blood vessel hemangioma | Heart |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Blood vessel hemangioma | Liver | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangioma | Heart | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangioma | Liver | urethane (ethyl carbamate) |
0 - 65 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangioma | Heart | urethane (ethyl carbamate) |
0 - 5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangiosarcoma | Spleen |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Blood vessel hemangiosarcoma | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Blood vessel hemangiosarcoma | Abdominal cavity |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Blood vessel hemangiosarcoma | Liver | urethane (ethyl carbamate) |
0 - 40 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangiosarcoma | Spleen | urethane (ethyl carbamate) |
0 - 5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangiosarcoma | Abdominal cavity | urethane (ethyl carbamate) |
0 - 5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangiosarcoma | Abdominal cavity | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangiosarcoma | Spleen | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hemangiosarcoma | Liver | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hyperplasia | Liver | urethane (ethyl carbamate) |
10 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Blood vessel hyperplasia | Heart | urethane (ethyl carbamate) |
5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Bone osteosarcoma | Bone - Jaw |
0 |
1.9 |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 |
||||
Bone osteosarcoma | Bone |
0 - 6.7 |
0 - 0.5 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Bone osteosarcoma | Bone | benzene |
0 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Bone osteosarcoma | Bone | Cyclosporin A |
0 - 6.7 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
CNS - Brain - Astrocyte astrocytoma | CNS - Brain - Astrocyte |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
CNS - Brain - Astrocyte astrocytoma | CNS - Brain - Astrocyte | Cyclosporin A |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
CNS - Meninges meningioma | CNS - Meninges |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
CNS - Meninges meningioma | CNS - Meninges | phenacetin |
0 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Connective tissue - Fibroblast fibrosarcoma | Urinary bladder |
0 |
0.9 |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 |
||||
Connective tissue - Fibroblast fibrosarcoma | CNS - Meninges |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Connective tissue - Fibroblast fibrosarcoma | CNS - Meninges | cyclophosphamide (Cytoxan) |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Connective tissue - Fibroblast fibrosarcoma | Subcutis |
0 - 13.3 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Connective tissue - Fibroblast fibrosarcoma | Subcutis | Cyclosporin A |
0 - 13.3 |
0 - 13.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Connective tissue - Fibroblast fibrosarcoma | Subcutis | chloroform |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Forestomach hyperplasia | Forestomach | d-limonene |
85 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Forestomach hyperplasia | Forestomach | ampicillin |
observed |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Kidney transitional cell hyperplasia | Kidney |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Kidney transitional cell hyperplasia | Kidney | diethylhexylphthalate (DEHP) |
0 - 20 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Kidney transitional cell papilloma | Kidney |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Kidney transitional cell papilloma | Kidney | diethylhexylphthalate (DEHP) |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte - Lymphocyte hyperplasia | Thymus |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte - Lymphocyte hyperplasia | Thymus | benzene |
13.3 |
20 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Thymus |
6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | Thymus | cyclophosphamide (Cytoxan) |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic | Leukocyte - Myelocyte (Granulocyte) |
0 |
0 - 0.9 |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic | Leukocyte - Myelocyte (Granulocyte) | cyclophosphamide (Cytoxan) |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte leukemia | Leukocyte |
2.9 |
1.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte lymphoma | Thymus |
0 - 13.3 |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte lymphoma | Thymus | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Leukocyte lymphoma | Thymus | urethane (ethyl carbamate) |
0 - 15 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 Sites of Metastasis: (Unspecified organ) |
||||
Leukocyte lymphoma | Leukocyte |
0 - 20 |
0 - 13.3 |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Leukocyte lymphoma | Leukocyte | melphalan (L-phenylalanine mustard) (L-sarcolysin) |
observed |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 |
||||
Leukocyte lymphoma | Leukocyte | benzene |
6.7 |
20 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte lymphoma | Thymus | benzene |
0 |
6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte lymphoma | Leukocyte | cyclophosphamide (Cytoxan) |
0 - 53.3 |
0 - 26.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte lymphoma | Thymus | phenacetin |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte lymphoma | Leukocyte | Cyclosporin A |
0 - 53.3 |
0 - 53.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Leukocyte lymphoma | Leukocyte | metaproterenol |
0 - 6.7 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Liver adenoma | Liver |
0 |
0.2 - 6.7 |
0 |
References: Dass SB, Cancer Lett 1999 Aug 23;143(1):81-5 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Liver adenoma | Liver | dimethylnitrosamine (DMN) |
0 - 1.1 |
References: Dass SB, Cancer Lett 1999 Aug 23;143(1):81-5 |
||||
Liver adenoma | Liver | 6-nitrochrysene (6-NC) |
0 - 20 |
References: Dass SB, Cancer Lett 1999 Aug 23;143(1):81-5 |
||||
Liver adenoma | Liver | 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) |
5.9 - 13.3 |
References: Dass SB, Cancer Lett 1999 Aug 23;143(1):81-5 |
||||
Liver adenoma | Liver | chloroform |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Liver carcinoma | Liver |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Liver carcinoma | Liver | chloroform |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Liver hepatocellular carcinoma | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Liver hepatocellular carcinoma | Liver | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Liver hepatocellular carcinoma | Liver | urethane (ethyl carbamate) |
0 - 20 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Liver hyperplasia - oval cell | Liver | urethane (ethyl carbamate) |
0 - 10 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Liver hyperplasia - oval cell | Liver | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Liver hyperplasia - oval cell | Liver |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Liver preneoplastic lesion | Liver | diethylnitrosamine (DEN) |
observed |
References: Finnberg N, Cancer Lett 2004 Apr 30;207(2):149-55 |
||||
Liver tumor | Liver |
0 |
6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Liver tumor | Liver | chloroform |
0 - 13.3 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Lung adenoma | Lung |
0.5 - 6.7 |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 ⋅ Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Lung adenoma | Lung | urethane (ethyl carbamate) |
0 - 25 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Lung adenoma | Lung | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Lung adenoma | Lung | Cyclosporin A |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Lung adenoma | Lung | chloroform |
0 - 6.7 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Lung hyperplasia | Lung |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Lung hyperplasia | Lung | chloroform |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Mesodermal cell/mesoblast sarcoma | Subcutis |
0 - 13.3 |
0 - 6.7 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 ⋅ Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Mesodermal cell/mesoblast sarcoma | Subcutis | d-limonene |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Mesodermal cell/mesoblast sarcoma | Subcutis | urethane (ethyl carbamate) |
0 - 5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Mesodermal cell/mesoblast sarcoma | CNS - Meninges |
0.2 - 0.9 |
0 |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Mesodermal cell/mesoblast sarcoma | Subcutis | melphalan (L-phenylalanine mustard) (L-sarcolysin) |
observed |
References: Mahler JF, Toxicol Pathol 1998 Jul-Aug;26(4):501-11 Sites of Metastasis: Abdominal wall , Peritoneal cavity |
||||
Mesodermal cell/mesoblast sarcoma | Prostate gland |
0.2 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Mesodermal cell/mesoblast sarcoma | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Mesodermal cell/mesoblast sarcoma | Urinary bladder | p-cresidine |
0 |
6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Mesodermal cell/mesoblast sarcoma | Subcutis | benzene |
0 - 6.7 |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Mesodermal cell/mesoblast sarcoma | Subcutis | cyclophosphamide (Cytoxan) |
0 - 13.3 |
0 - 13.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Mesodermal cell/mesoblast sarcoma | Subcutis | phenacetin |
6.7 - 26.7 |
6.7 - 13.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Muscle - Smooth leiomyosarcoma | Prostate gland |
0.2 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Muscle - Striated - Skeletal rhabdomyosarcoma | Lung |
0.2 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Muscle - Striated - Skeletal rhabdomyosarcoma | Muscle - Striated - Skeletal |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Muscle - Striated - Skeletal rhabdomyosarcoma | Muscle - Striated - Skeletal | metaproterenol |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Neuroblast neuroblastoma - olfactory | Nose - Nasal cavity |
0 - 0.2 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Neuroblast neuroblastoma - olfactory | Nose - Nasal cavity | Cyclosporin A |
0 - 6.7 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Oral cavity squamous cell carcinoma | Oral cavity |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Oral cavity squamous cell carcinoma | Oral cavity | benzene |
0 |
6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Pancreas carcinoma | Pancreas |
0 |
0.2 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland - Pars distalis adenoma | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland - Pars distalis adenoma | Pituitary gland - Pars distalis | diethylstilbestrol (DES) |
13.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland - Pars distalis hyperplasia | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland - Pars distalis hyperplasia | Pituitary gland - Pars distalis | 17beta-estradiol (E2) |
0 - 80 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland - Pars distalis hyperplasia - diffuse | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland - Pars distalis hyperplasia - diffuse | Pituitary gland - Pars distalis | diethylstilbestrol (DES) |
93.3 - 100 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland - Pars distalis hyperplasia - nodular | Pituitary gland - Pars distalis |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland - Pars distalis hyperplasia - nodular | Pituitary gland - Pars distalis | diethylstilbestrol (DES) |
33.3 - 53.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland - Pars intermedia adenoma | Pituitary gland - Pars intermedia |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland - Pars intermedia adenoma | Pituitary gland - Pars intermedia | diethylstilbestrol (DES) |
6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland - Pars intermedia hyperplasia - diffuse | Pituitary gland - Pars intermedia |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland - Pars intermedia hyperplasia - diffuse | Pituitary gland - Pars intermedia | diethylstilbestrol (DES) |
93.3 - 100 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland adenoma | Pituitary gland |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland adenoma | Pituitary gland | 17beta-estradiol (E2) |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Pituitary gland hyperplasia - focal | Pituitary gland |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Pituitary gland hyperplasia - focal | Pituitary gland | 17beta-estradiol (E2) |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Prostate gland adenoma | Prostate gland |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Prostate gland adenoma | Prostate gland | urethane (ethyl carbamate) |
0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Prostate gland adenoma | Prostate gland | d-limonene |
5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
Prostate gland hyperplasia - focal | Prostate gland |
20 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
|||||
Stomach - Glandular hyperplasia | Stomach - Glandular | ampicillin |
observed |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Testis - Leydig cell (Interstitial cell) hyperplasia | Testis - Leydig cell (Interstitial cell) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Testis - Leydig cell (Interstitial cell) hyperplasia | Testis - Leydig cell (Interstitial cell) | diethylstilbestrol (DES) |
26.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Testis - Leydig cell (Interstitial cell) tumor | Testis - Leydig cell (Interstitial cell) |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Testis - Leydig cell (Interstitial cell) tumor | Testis - Leydig cell (Interstitial cell) | diethylstilbestrol (DES) |
0 - 13.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Thymus hyperplasia - atypical | Thymus |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Thymus hyperplasia - atypical | Thymus | benzene |
0 |
26.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Thyroid gland - Follicular cell hyperplasia | Thyroid gland - Follicular cell | sulfamethoxazole (SMX) |
observed |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Ureter hyperplasia | Ureter |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Ureter hyperplasia | Ureter | diethylhexylphthalate (DEHP) |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder atypia | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder atypia | Urinary bladder | p-cresidine |
33.3 |
40 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder dysplasia | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder dysplasia | Urinary bladder | p-cresidine |
6.7 |
0 - 46.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder hyperplasia | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder hyperplasia | Urinary bladder | p-cresidine |
73.3 - 100 |
100 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder metaplasia - squamous | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder metaplasia - squamous | Urinary bladder | p-cresidine |
26.7 |
53.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder neoplasm | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder neoplasm | Urinary bladder | p-cresidine |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder papilloma | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder papilloma | Urinary bladder | p-cresidine |
13.3 |
26.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder squamous cell carcinoma | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder squamous cell carcinoma | Urinary bladder | p-cresidine |
13.3 |
33.3 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder transitional cell carcinoma | Urinary bladder |
0 |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
Urinary bladder transitional cell carcinoma | Urinary bladder | p-cresidine |
6.7 - 73.3 |
20 - 66.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Urinary bladder tumor | Urinary bladder | p-cresidine |
60 |
86.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||
Uterus - Endometrium - Stroma polyp | Uterus - Endometrium - Stroma |
0 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
|||||
Uterus - Endometrium - Stroma polyp | Uterus - Endometrium - Stroma | cyclophosphamide (Cytoxan) |
0 - 6.7 |
References: Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
(Unspecified organ) tumor | (Unspecified organ) |
6.0 - 11.3 |
0 - 8.0 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 ⋅ Storer RD, Toxicol Pathol 2001;29 Suppl():30-50 |
||||
(Unspecified organ) tumor | (Unspecified organ) | urethane (ethyl carbamate) |
0 - 100 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |
||||
(Unspecified organ) tumor | (Unspecified organ) | d-limonene |
5 |
References: Carmichael NG, Environ Health Perspect 2000 Jan;108(1):61-5 |