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Strain SummaryB6.129S6-Tgfb1^tm1N/+

Strain Name	B6.129S6-Tgfb1^tm1N/+
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	HT • TGF-β1^+/-
Description	Heterozygous mice. These mice have been backcrossed onto C57BL/6NCr. The targeted mutant allele was originally generated using 129S6/SvEvTac-derived ES cells.
Strain Genetics	List all models in MMHCdb carrying the Tgfb1^tm1N allele Tgfb1^tm1N / Tgfb1⁺

Models
17 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Liver hepatocellular adenoma	Liver			0			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hepatocellular adenoma	Liver	diethylnitrosamine (DEN)		observed - 20			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hepatocellular adenoma	Liver	phenobarbital (PB) ⋅ diethylnitrosamine (DEN)		0 - 29			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hepatocellular carcinoma	Liver			0			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hepatocellular carcinoma	Liver	diethylnitrosamine (DEN)		0			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hepatocellular carcinoma	Liver	phenobarbital (PB) ⋅ diethylnitrosamine (DEN)		0 - 25			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hepatocellular tumor	Liver	diethylnitrosamine (DEN)		44			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Liver hyperplasia	Liver			0			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus adenoma	Lung - Alveolus			5.3			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus adenoma	Lung - Alveolus	diethylnitrosamine (DEN)		0 - observed			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus adenoma	Lung - Alveolus	phenobarbital (PB) ⋅ diethylnitrosamine (DEN)		0			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus carcinoma	Lung - Alveolus			0			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus carcinoma	Lung - Alveolus	diethylnitrosamine (DEN)		0 - 29			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus carcinoma	Lung - Alveolus	phenobarbital (PB) ⋅ diethylnitrosamine (DEN)		0 - 4.8			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus tumor	Lung - Alveolus	diethylnitrosamine (DEN)		79			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung - Alveolus tumor	Lung - Alveolus	phenobarbital (PB) ⋅ diethylnitrosamine (DEN)		52			References: Tang B, Nat Med 1998 Jul;4(7):802-7
Lung hyperplasia	Lung			0			References: Tang B, Nat Med 1998 Jul;4(7):802-7