Strain Summary129S1-Actbtm2(Tag)Arge

Strain Name

129S1-Actbtm2(Tag)Arge

Strain Type(s)

targeted mutation (knock-in)

Strain Synonym(s)

129S1-Actbtm1(Tag)Arge  •  b-actinSVER/SVER

Description

Homozygous mice. The genetic background was 129S1/Sv.

Strain Genetics

Actbtm2(Tag)Arge / Actbtm2(Tag)Arge

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

high

References: Politi K, Oncogene 2004 Feb 26;23(8):1558-65

Sites of Metastasis: Abdominal cavity

Mesodermal cell/mesoblast sarcoma - undifferentiated Mesodermal cell/mesoblast

100

References: Politi K, Oncogene 2004 Feb 26;23(8):1558-65

Mesodermal cell/mesoblast sarcoma - undifferentiated Liver

high

References: Politi K, Oncogene 2004 Feb 26;23(8):1558-65

Mesodermal cell/mesoblast sarcoma - undifferentiated Spleen

high

References: Politi K, Oncogene 2004 Feb 26;23(8):1558-65

Mesodermal cell/mesoblast sarcoma - undifferentiated Thoracic cavity

high

References: Politi K, Oncogene 2004 Feb 26;23(8):1558-65