Strain SummaryFVB.Cg-Tg(KRT14-HPV16)wt1Dh

Strain Name

 FVB.Cg-Tg(KRT14-HPV16)wt1Dh

Strain Type(s)

 congenic  •  transgenic

Strain Synonym(s)

 HPV16/E2  •  K14-HPV16

Description

 These mice were backcrossed to FVB/N. The transgenic line was originally generated on a B6D2F2 genetic background.

Strain Genetics

 Tg(KRT14-HPV16)wt1Dh

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Uterus - Cervix cervical intraepithelial neoplasia (CIN) Uterus - Cervix 17beta-estradiol (E2)

observed

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Uterus - Cervix cervical intraepithelial neoplasia (CIN) Uterus - Cervix 17beta-estradiol (E2)   ⋅   batimastat (BB-94)

observed

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Uterus - Cervix cervical intraepithelial neoplasia (CIN) Uterus - Cervix 17beta-estradiol (E2)   ⋅   zoledronic acid

observed

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Uterus - Cervix squamous cell carcinoma Uterus - Cervix 17beta-estradiol (E2)

very high - 90

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Sites of Metastasis: not (Unspecified organ)
Uterus - Cervix squamous cell carcinoma Uterus - Cervix 17beta-estradiol (E2)   ⋅   batimastat (BB-94)

observed

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Uterus - Cervix squamous cell carcinoma Uterus - Cervix 17beta-estradiol (E2)   ⋅   zoledronic acid

observed - very high

References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33