Strain SummaryFVB/N-Mmp9^tm1Tvu Tg(KRT14-HPV16)wt1Dh

Strain Name	FVB/N-Mmp9^tm1Tvu Tg(KRT14-HPV16)wt1Dh
Strain Type(s)	targeted mutation (knockout) • transgenic
Strain Synonym(s)	FVB.Cg-Mmp9^tm1Tvu Tg(KRT14-HPV16)wt1Dh • HPV/E₂-MMP-9?null • HPV/E₂-MMP-9^-/- • K14-HPV16 MMP-9^?/?
Description	Compound mutant mice. These mice are the product of an intercross between strains on a predominantly FVB/N background.
Strain Genetics	List all models in MMHCdb carrying the Tg(KRT14-HPV16)wt1Dh allele Tg(KRT14-HPV16)wt1Dh
	List all models in MMHCdb carrying the Mmp9^tm1Tvu allele Mmp9^tm1Tvu / Mmp9^tm1Tvu

Models
2 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Uterus - Cervix cervical intraepithelial neoplasia (CIN)	Uterus - Cervix	17beta-estradiol (E2)	observed				References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33
Uterus - Cervix squamous cell carcinoma	Uterus - Cervix	17beta-estradiol (E2)	moderate				References: Giraudo E, J Clin Invest 2004 Sep;114(5):623-33

Models