Strain SummaryFVB/N-Tg(MMTV-Notch4)3Rnc

Strain Name	FVB/N-Tg(MMTV-Notch4)3Rnc
Strain Type(s)	transgenic
Strain Synonym(s)	FVB/N-TgN(MMTVInt3)3Rnc • FVB/N-TgN(MMTV-Notch4)3Rnc • int-3 • MMTV-int-3
Strain Genetics	List all models in MMHCdb carrying the Tg(MMTV-Notch4)3Rnc allele Tg(MMTV-Notch4)3Rnc

Models
10 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Epididymis hyperplasia	Epididymis			100			References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Eye - Harderian gland hyperplasia	Eye - Harderian gland					observed	References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Eye - Lacrimal gland hyperplasia	Eye - Lacrimal gland					observed	References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Leukocyte - Lymphoblast lymphoma - lymphoblastic	Thymus			observed			References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Mammary gland adenocarcinoma	Mammary gland		observed	observed		observed	References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55 Sites of Metastasis: Lung
Mammary gland hyperplasia	Mammary gland		observed			observed	References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Nose - Nasal cavity - Nasal gland hyperplasia	Nose - Nasal cavity - Nasal gland					observed	References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Prostate gland - Anterior lobe hyperplasia	Prostate gland - Anterior lobe			observed			References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Salivary gland adenocarcinoma	Salivary gland		observed	observed			References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55
Salivary gland hyperplasia	Salivary gland		very high	very high			References: Jhappan C, Genes Dev 1992 Mar;6(3):345-55

Models