Strain SummaryB6;129S-Nkx3-1^tm1Mms/? Pten^tm1Rps/+

Strain Name	B6;129S-Nkx3-1^tm1Mms/? Pten^tm1Rps/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Nkx3.1^{+/- or -/-}; Pten^+/-; p27^+/+
Description	Mice heterozygous or homozygous for the Nkx3-1^tm1Mms, author pooled both types. Heterozygous for Pten^tm1Rps mutation. The genetic background was a mix of C57BL/6J, 129S1/Sv, and 129S3/SvImJ.
Strain Genetics	List all models in MMHCdb carrying the Pten^tm1Rps allele Pten^tm1Rps / Pten⁺
	Cdkn1b⁺ / Cdkn1b⁺
	List all models in MMHCdb carrying the Nkx3-1^tm1Mms allele Nkx3-1^tm1Mms / Nkx3-1^?

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Prostate gland hyperplasia	Prostate gland			0 - 39			References: Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9
Prostate gland prostatic intraepithelial neoplasia - high grade (HGPIN)	Prostate gland			33 - 73			References: Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9
Prostate gland prostatic intraepithelial neoplasia - low grade (LGPIN)	Prostate gland			27 - 28			References: Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9

Models