Strain SummaryB6;129S-Nkx3-1^tm1Mms Pten^tm1Rps/+

Strain Name	B6;129S-Nkx3-1^tm1Mms Pten^tm1Rps/+
Strain Type(s)	targeted mutation (knockout)
Strain Synonym(s)	Nkx3.1-/-; Pten^+/-; p27^+/+
Description	Mice were homozygous for Nkx3-1^tm1Mms and heterozygous for Pten^tm1Rps. The genetic background was a mix of C57BL/6J, 129S1/Sv, and 129S3/SvImJ.
Strain Genetics	List all models in MMHCdb carrying the Pten^tm1Rps allele Pten^tm1Rps / Pten⁺
	List all models in MMHCdb carrying the Nkx3-1^tm1Mms allele Nkx3-1^tm1Mms / Nkx3-1^tm1Mms

Models
1 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Prostate gland - Dorsolateral lobe prostatic intraepithelial neoplasia - high grade (HGPIN)	Prostate gland - Dorsolateral lobe			observed			References: Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9 5 pathology image(s)

Models