Strain SummaryB6;129S-Cdkn1btm1Ako/+ Nkx3-1tm1Mms

Strain Name

B6;129S-Cdkn1btm1Ako/+ Nkx3-1tm1Mms

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

B6;129S-Nkx3-1tm1Mms Cdkn1btm1Ako/+  •  Nkx3.1-/-; Pten+/+; p27+/-

Description

Mice were homozygous for Nkx3-1tm1Mms and heterozygous for Cdkn1btm1Ako. The genetic background was a mix of C57BL/6J, 129S1/Sv, and 129S3/SvImJ.

Strain Genetics

Cdkn1btm1Ako / Cdkn1b+
Nkx3-1tm1Mms / Nkx3-1tm1Mms

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Prostate gland - Dorsolateral lobe prostatic intraepithelial neoplasia (PIN) Prostate gland - Dorsolateral lobe

observed

References: Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9

1 pathology image(s)