Strain SummaryB6;129S-Cdkn1btm1Ako/+ Ptentm1Rps/+
Strain Name |
B6;129S-Cdkn1btm1Ako/+ Ptentm1Rps/+ |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
Nkx3.1+/+; Pten+/-; p27+/- |
Description |
Mice were heterozygous for Cdkn1btm1Ako and Ptentm1Rps. The genetic background was a mix of C57BL/6J, 129S1/Sv, and 129S3/SvImJ. |
Strain Genetics |
Cdkn1btm1Ako / Cdkn1b+ |
| Ptentm1Rps / Pten+ |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Prostate gland - Dorsolateral lobe prostatic intraepithelial neoplasia (PIN) | Prostate gland - Dorsolateral lobe |
observed |
References: Gao H, Proc Natl Acad Sci U S A 2004 Dec 7;101(49):17204-9 1 pathology image(s) |
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