Strain SummaryBALB/cJ-Brca1tm1Bhk/+ Trp53tm1Tyj/+
Strain Name |
BALB/cJ-Brca1tm1Bhk/+ Trp53tm1Tyj/+ |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
BALB_BRCA1het_p53het • BALBc_Brca1het_p53het • BRCA1+/-, P53+/- • Brca1tm1Bhk/+ ; Trp53tm1Tyj/+ • Brca1+/-;p53+/- • Brca1+/?, Trp53+/? |
Description |
Double heterozygous mice. The genetic background of these mice was predominantly BALB/cJ. It also contained some 129P2/OlaHsd and some 129S2/SvPas and possibly some other strain(s). |
Strain Genetics |
Trp53tm1Tyj / Trp53+ |
Brca1tm1Bhk / Brca1+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Mammary gland carcinoma | Mammary gland | gamma-radiation |
observed |
References: Herschkowitz JI, Genome Biol 2007;8(5):R76 |