Strain SummaryB6.129S2-Cdkn1a^tm1Tyj

Strain Name	B6.129S2-Cdkn1a^tm1Tyj
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	p21-/- • p21-/-p27+/+
Description	Homozygous mice. These mice had been backcrossed to C57BL/6J.
Strain Genetics	List all models in MMHCdb carrying the Cdkn1a^tm1Tyj allele Cdkn1a^tm1Tyj / Cdkn1a^tm1Tyj

Models
9 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla					0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Blood vessel hemangioma	Blood vessel					10	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Lymphocyte - B-lymphocyte lymphoma	Leukocyte - Lymphocyte - B-lymphocyte					5.0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Lymphocyte - T-lymphocyte lymphoma	Thymus	gamma-radiation				33	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Leukocyte - Monocyte - Macrophage - Histiocyte					30	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Lung adenoma	Lung					5.0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Pituitary gland adenoma	Pituitary gland					5.0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Thyroid gland adenoma	Thyroid gland					0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
(Unspecified organ) tumor	(Unspecified organ)					55	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42

Models