Strain SummaryB6.129S4-Cdkn1b^tm1Mlf

Strain Name	B6.129S4-Cdkn1b^tm1Mlf
Strain Type(s)	congenic • targeted mutation (knockout)
Strain Synonym(s)	p21+/+p27-/- • p27-/-
Description	Homozygous mice. These mice had been backcrossed to C57BL/6J.
Strain Genetics	List all models in MMHCdb carrying the Cdkn1b^tm1Mlf allele Cdkn1b^tm1Mlf / Cdkn1b^tm1Mlf

Models
9 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla					16.7	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Blood vessel hemangioma	Blood vessel					0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum					5.6	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Lymphocyte - B-lymphocyte lymphoma	Leukocyte - Lymphocyte - B-lymphocyte					0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Lymphocyte - T-lymphocyte lymphoma	Thymus	gamma-radiation				100	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Leukocyte - Monocyte - Macrophage - Histiocyte					0	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Pituitary gland adenoma	Pituitary gland					27.8	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Thyroid gland adenoma	Thyroid gland					5.6	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
(Unspecified organ) tumor	(Unspecified organ)					50 - 55.6	References: Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42

Models