Strain SummaryB6;FVB-Gt(ROSA)26Sor^{tm1(tTA,tetO-Mir155)Fjsl}/Gt(ROSA)26Sor Tg(Nes-cre)1Wmz

Strain Name	B6;FVB-Gt(ROSA)26Sor^{tm1(tTA,tetO-Mir155)Fjsl}/Gt(ROSA)26Sor Tg(Nes-cre)1Wmz
Strain Type(s)	targeted mutation (knock-in) • transgenic
Strain Synonym(s)	NesCre8; mir-155^LSLtTA
Description	Heterozygous, transgenic mice on a mixed C57BL/6, FVB/NJ background with possible contributions from C57BL/6J and SJL/J.
Strain Genetics	List all models in MMHCdb carrying the Gt(ROSA)26Sor^{tm1(tTA,tetO-Mir155)Fjsl} allele List all models in MMHCdb carrying the Gt(ROSA)26Sor allele Gt(ROSA)26Sor^{tm1(tTA,tetO-Mir155)Fjsl} / Gt(ROSA)26Sor
	List all models in MMHCdb carrying the Tg(Nes-cre)1Wmz allele Tg(Nes-cre)1Wmz

Models
6 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
CNS - Brain tumor	CNS - Brain	doxycycline				0	References: Babar IA, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):E1695-704
Leukocyte - Lymphocyte - B-lymphocyte lymphoma	Leukocyte - Lymphocyte - B-lymphocyte	doxycycline				observed	References: Babar IA, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):E1695-704
Liver hyperplasia	Liver	doxycycline				observed	References: Babar IA, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):E1695-704
Lymph node hyperplasia	Lymph node	doxycycline				0 - observed	References: Babar IA, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):E1695-704
Spleen hyperplasia	Spleen	doxycycline				0 - observed	References: Babar IA, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):E1695-704
Thymus hyperplasia	Thymus	doxycycline				observed	References: Babar IA, Proc Natl Acad Sci U S A 2012 Jun 26;109(26):E1695-704

Models