Strain Summary[not specified]-Trp53tm1Brn

Strain Name

 [not specified]-Trp53tm1Brn

Strain Type(s)

 targeted mutation (conditional)

Strain Synonym(s)

 p53loxP/loxP

Description

 Homozygous mice. The genetic background of these mice was not specified but included at least some 129P2/OlaHsd. It may possibly also have involved FVB/N.

Strain Genetics

 Trp53tm1Brn / Trp53tm1Brn

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Mesodermal cell/mesoblast sarcoma - pleomorphic - undifferentiated Mesodermal cell/mesoblast Ad5-CMV-Cre (AdCre) (AdCMVCre)

3.0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Sites of Metastasis: Lung
Muscle - Smooth leiomyosarcoma Muscle - Smooth Ad5-CMV-Cre (AdCre) (AdCMVCre)

3.0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal Ad5-CMV-Cre (AdCre) (AdCMVCre)

3.0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Skin dermatofibroma Skin Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Subcutis tumor Subcutis Ad5-CMV-Cre (AdCre) (AdCMVCre)

9.1 - 10

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

Subcutis tumor Subcutis Ad5-CMV-LacZ (AdCMVLacZ)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58

(Unspecified organ) angiosarcoma (Unspecified organ) Ad5-CMV-Cre (AdCre) (AdCMVCre)

0

References: Choi J, Am J Pathol 2010 Nov;177(5):2645-58